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Science 15 December 1972:
Vol. 178. no. 4066, pp. 1204 - 1205
DOI: 10.1126/science.178.4066.1204
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Articles

Collagen Synthesis in Xenopus Oocytes after Injection of Nuclear RNA of Frog Embryos

J. W. Rollins 1 and R. A. Flickinger 1

1 Department of Biology, State University of New York, Buffalo 14214

A messenger RNA fraction from polysomes of frog larvae or RNA preparations from isolated nuclei of developing frog embryos were injected into growing Xenopus laevis oocytes that were incubated with labeled proline. Column chromatography of protein hydrolyzates revealed labeled hydroxyproline after injection of the messenger RNA fraction and neurula nuclear RNA, indicating that the injected material had promoted collagen synthesis.

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Science. ISSN 0036-8075 (print), 1095-9203 (online)