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Science 17 November 1972:
Vol. 178. no. 4062, pp. 767 - 768
DOI: 10.1126/science.178.4062.767
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Articles

Inactivation of Horizontal Cells in Turtle Retina by Glutamate and Aspartate

Luigi Cervetto 1 and Edward F. MacNichol Jr. 1

1 Laboratory of Neurophysiology, National Institute of Neurological Diseases and Stroke, Bethesda, Maryland 20014

Glutamate and aspartate completely suppress the activity of horizontal cells but only partially affect the response of receptor cells to light. The changes observed in the receptor responses are consistent with the interruption of a synaptically mediated process rather than with a direct action on the receptor membrane.


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