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Science 22 September 1972:
Vol. 177. no. 4054, pp. 1119 - 1121
DOI: 10.1126/science.177.4054.1119
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Articles

Reverse Transcriptases of Primate Viruses as Immunological Markers

Edward M. Scolnick 1, Wade P. Parks 1, and George J. Todaro 1

1 Viral Leukemia and Lymphoma Branch and Viral Carcinogenesis Branch, National Cancer Institute, Bethesda, Maryland 20014

Antibodies were prepared against the DNA polymerases (reverse transcriptases) of three potentially oncogenic RNA viruses of primates. Two type C viruses, isolated from a woolly monkey fibrosarcoma and from a gibbon ape lymphosarcoma, have polymerases that are immunologically related to each other and are distinct from the type C viruses isolated from other mammals.


THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES:
Type C RNA tumor virus isolated from cultured human acute myelogenous leukemia cells.
R. Gallagher and R. Gallo (1975)
Science 187, 350-353
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Relationships between Components in Primate RNA Tumor Viruses and in the Cytoplasm of Human Leukemic Cells: Implications to Leukemogenesis.
R. C. Gallo, R. E. Gallagher, N. R. Miller, H. Mondal, W. C. Saxinger, R. J. Mayer, R. G. Smith, and D. H. Gillespie (1974)
Cold Spring Harb Symp Quant Biol 39, 933-961
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Mammalian Cells in Culture Frequently Release Type C Viruses.
M. M. Lieber, R. E. Benveniste, D. M. Livingston, and G. J. Todaro (1973)
Science 182, 56-59
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