Note to users. If you're seeing this message, it means that your browser cannot find this page's style/presentation instructions -- or possibly that you are using a browser that does not support current Web standards. Find out more about why this message is appearing, and what you can do to make your experience of our site the best it can be.

Science 22 September 1972:
Vol. 177. no. 4054, pp. 1111 - 1114
DOI: 10.1126/science.177.4054.1111
Prev | Table of Contents | Next

Articles

DNA Polymerases from RNA Tumor Viruses and Human Cells: Inhibition by Polyuridylic Acid

John W. Abrell 1, R. Graham Smith 2, Marjorie S. Robert 2, and Robert C. Gallo 2

1 Bionetics Research Laboratories, Bethesda, Maryland 20014
2 Laboratory of Tumor Cell Biology, National Cancer Institute, Bethesda

Polyuridylic acid inhibited DNA polymerases purified from three species of oncornaviruses as well as three out of seven DNA polymerases purified from cells. Viral and cellular DNA polymerases could not be distinguished by polyuridylic acid inhibition, but were easily distinguished by their template preferences in the presence of magnesium.

To Advertise     Find Products

Science. ISSN 0036-8075 (print), 1095-9203 (online)