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Science 30 June 1972:
Vol. 176. no. 4042, pp. 1432 - 1434
DOI: 10.1126/science.176.4042.1432
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Articles

Cytochalasin B: Inhibition of D-2-Deoxyglucose Transport into Leukocytes and Fibroblasts

Sally H. Zigmond 1 and James G. Hirsch 1

1 Rockefeller University, New York 10021

Cytochalasin B inhibits transport of D-2-deoxyglucose and of glucosamine into kukocytes, but does not impair uptake of kucine by these cells. This inhibitory action is rapid and reversible, and results in suppression of glycolysis. Cytochalasin B also blocks transport of D-2-deoxyglucose, but not of leucine, into mouse L strain fibroblasts.


THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES:
Vasopressin: Possible Role of Microtubules and Microfilaments in Its Action.
A. Taylor, M. Mamelak, E. Reaven, and R. Maffly (1973)
Science 181, 347-350
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Science. ISSN 0036-8075 (print), 1095-9203 (online)