Note to users. If you're seeing this message, it means that your browser cannot find this page's style/presentation instructions -- or possibly that you are using a browser that does not support current Web standards. Find out more about why this message is appearing, and what you can do to make your experience of our site the best it can be.


Science 24 December 1971:
Vol. 174. no. 4016, pp. 1354 - 1356
DOI: 10.1126/science.174.4016.1354

Articles

Stage 4 Sleep: Influence of Time Course Variables

W. B. Webb 1 and H. W. Agnew Jr. 1

1 Department of Psychology, University of Florida, Gainesville 32601

Age, length of prior wakefulness, length of time asleep, and a circadian influence all affect stage 4 sleep. The amount of stage 4 sleep decreases as subject's age increases and as time asleep increases. Longer periods of wakefulness before sleep result in greater amounts of stage 4 sleep in the first 3 hours of sleep. Sleep periods that begin at times other than the regular onset time tend to produce less stage 4 sleep; this decrease suggests a circadian effect.


THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES:
The adolescent decline of NREM delta, an indicator of brain maturation, is linked to age and sex but not to pubertal stage.
I. Feinberg, L. M. Higgins, W. Y. Khaw, and I. G. Campbell (2006)
Am J Physiol Regulatory Integrative Comp Physiol 291, R1724-R1729
   Abstract »    Full Text »    PDF »
A functional genetic variation of adenosine deaminase affects the duration and intensity of deep sleep in humans.
J. V. Retey, M. Adam, E. Honegger, R. Khatami, U. F. O. Luhmann, H. H. Jung, W. Berger, and H.-P. Landolt (2005)
PNAS 102, 15676-15681
   Abstract »    Full Text »    PDF »
Circadian temperature and melatonin rhythms, sleep, and neurobehavioral function in humans living on a 20-h day.
J. K. Wyatt, A. R.-D. Cecco, C. A. Czeisler, and D.-J. Dijk (1999)
Am J Physiol Regulatory Integrative Comp Physiol 277, R1152-R1163
   Abstract »    Full Text »    PDF »
Ageing and the circadian and homeostatic regulation of human sleep during forced desynchrony of rest, melatonin and temperature rhythms.
D.-J. Dijk, J. F Duffy, E. Riel, T. L Shanahan, and C. A Czeisler (1999)
J. Physiol. 516, 611-627
   Abstract »    Full Text »    PDF »
Experimental separation of time of day and homeostatic influences on sleep.
T. Akerstedt, K. Hume, D. Minors, and J. Waterhouse (1998)
Am J Physiol Regulatory Integrative Comp Physiol 274, R1162-R1168
   Abstract »    Full Text »    PDF »
Light Treatment for Sleep Disorders: Consensus Report: II. Basic Properties of Circadian Physiology and Sleep Regulation.
D.-J. Dijk, Z. Boulos, C. I. Eastman, A. J. Lewy, S. S. Campbell, and M. Terman (1995)
J Biol Rhythms 10, 113-125
   Abstract »    PDF »
EEG Power Density during Nap Sleep: Reflection of an Hourglass Measuring the Duration of Prior Wakefulness.
D. J. Dijk, D. G. M. Beersma, and S. Daan (1987)
J Biol Rhythms 2, 207-219
   Abstract »    PDF »
The Influence of Prior Wakefulness on REM Sleep.
J. B. Knowles, A. W. MacLean, C. Vetere, P. Young, L. Salem, M. Surridge-David, and M. Coulter (1987)
J Biol Rhythms 2, 81-93
   Abstract »    PDF »
Slow-Wave Sleep in Daytime and Nocturnal Sleep: An Estimate of the Time Course of "Process S".
J. B. Knowles, A. W. MacLean, L. Salem, C. Vetere, and M. Coulter (1986)
J Biol Rhythms 1, 303-308
   Abstract »    PDF »
Computer-Detected Patterns of Electroencephalographic Delta Activity During and After Extended Sleep.
I. FEINBERG, G. FEIN, and T. C. FLOYD (1982)
Science 215, 1131-1133
   Abstract »    PDF »
Slow-wave sleep: a recovery period after exercise.
C. Shapiro, R Bortz, D Mitchell, P Bartel, and P Jooste (1981)
Science 214, 1253-1254
   Abstract »    PDF »
Flurazepam Effects on Sleep EEG: Visual, Computer, and Cycle Analysis.
I. Feinberg, G. Fein, J. M. Walker, L. J. Price, T. C. Floyd, and J. D. March (1979)
Arch Gen Psychiatry 36, 95-102
   Abstract »    PDF »
Flurazepam effects on slow-wave sleep: stage 4 suppressed but number of delta waves constant.
I Feinberg, G Fein, J. Walker, L. Price, T. Floyd, and J. March (1977)
Science 198, 847-848
   Abstract »    PDF »



To Advertise     Find Products


Science. ISSN 0036-8075 (print), 1095-9203 (online)