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Science 8 October 1971:
Vol. 174. no. 4005, pp. 141 - 142
DOI: 10.1126/science.174.4005.141
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Articles

Kidney: Primary Source of Plasminogen after Acute Depletion in the Cat

Robert F. Highsmith 1 and Daniel L. Kline 1

1 Department of Physiology, University of Cincinnati College of Medicine, Cincinnati, Ohio 45219

The kidney was the primary source of plasminogen to restore normal plasma levels, after acute plasminogen depletion was produced by injection of streptokinase in cats. The concentration of plasminogen in the hepatic vein remained below that in the artery during the time when concentrations in the artery and renal vein were returning to normal.

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Science. ISSN 0036-8075 (print), 1095-9203 (online)