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Science 1 October 1971:
Vol. 174. no. 4004, pp. 64 - 66
DOI: 10.1126/science.174.4004.64
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Articles

Nonconversion of o,p'-DDT to p,p'-DDT in Rats, Sheep, Chickens, and Quail

Joel Bitman 1, Helene C. Cecil 1, and George F. Fries 1

1 Animal Science Research Division, Agricultural Research Service, Beltsville, Maryland 20705

The finding of appreciable quantities of p,p'-DDT after feeding o,p'-DDT to rats led to the proposal of a theory, that an isomeric metabolic conversion occurs. The presence of p,p'-DDT as an impurity in supposedly pure samples of o,p'-DDT is the correct explanation for the appearance of p,p'-DDT. Purified o,p'-DDT and 14C-labeled o,p'-DDT yielded no data to support the idea that o,p'-DDT is converted to the p,p'-DDT isomer.

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Science. ISSN 0036-8075 (print), 1095-9203 (online)