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Science 23 July 1971:
Vol. 173. no. 3994, pp. 347 - 349
DOI: 10.1126/science.173.3994.347
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Articles

Cerumen Genetics and Human Breast Cancer

Nicholas L. Petrakis 1

1 G. W. Hooper Foundation, Department of International Health, and Division of Ambulatory and Community Medicine, University of California, San Francisco 94122

International mortality and frequency rates for breast cancer seem to be associated with the frequency of the allele for wet-type cerumen. A preliminary retrospective case-control study in California indicates that phenotypically wet-type cerumen is found in Japanese women with breast cancer more often than in healthy Japanese women. Findings support the hypothesis that the apocrine system's genetically determined variation may influence susceptibility to breast cancer.


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Science. ISSN 0036-8075 (print), 1095-9203 (online)