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Science 16 July 1971:
Vol. 173. no. 3993, pp. 244 - 245
DOI: 10.1126/science.173.3993.244

Articles

Human Thymidine Kinase Gene Locus: Assignment to Chromosome 17 in a Hybrid of Man and Mouse Cells

O. J. Miller 1, P. W. Allderdice 1, D. A. Miller 1, W. R. Breg 2, and B. R. Migeon 3

1 Departments of Obstetrics and Gynecology and Human Genetics and Development, College of Physicians and Surgeons, Columbia University, New York 10032
2 Southbury Training School and Department of Pediatrics, Yale University School of Medicine, New Haven, Connecticut 06510
3 Department of Pediatrics, Johns Hopkins School of Medicine, Baltimore, Maryland 21205

The human chromosome retained in a hybrid clone derived from human cells and a moluse line deficiemt in thymidine kinase has the quinacrinefluorescence pattern characteristic of chromosome 17.


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