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Science 25 June 1971:
Vol. 172. no. 3990, pp. 1342 - 1344
DOI: 10.1126/science.172.3990.1342

Articles

Monosodium Glutamate: Absence of Hypothalamic Lesions after Ingestion by Newborn Primates

W. Ann Reynolds 1, N. Lemkey-Johnston 2, L. J. Filer Jr. 3, and R. M. Pitkin 4

1 Department of Anatomy, University of Illinois at the Medical Center, Chicago 60612
2 Illinois State Pediatric Institute, Chicago 60612
3 Department of Pediatrics, University of Iowa Hospitals, Iowa City 52240
4 Department of Obstetrics and Gynecology, University of Iowa Hospitals

After receiving monosodium glutamate by stomach tube, the brains of infant macaques were perfused for examination by light and electron microscopy. No morphological differences were observed in the hypothalamic regions of treated and control monkeys. However, inadequately fixed tissue had the same appearance as that of the previously reported brain lesion in a newborn monkey.


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