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Science 4 June 1971: Vol. 172. no. 3987, pp. 1044 - 1046 DOI: 10.1126/science.172.3987.1044
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Articles
Odor Incongruity and Chirality
Lester Friedman 1 and
John G. Miller 1
1 Department of Chemistry, Case Western Reserve University, Cleveland, Ohio 44106
The enantiomers R-(-)- and S-(+)-carvone are the organoleptic constituents in oil of spearmint and caraway, respectively. Their odor distinctiveness has been unambiguously demonstrated by chemical interconversion, independent synthesis, and resolution. Odor differences between other chiral isomers were also firmly established.
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