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Science 19 March 1971:
Vol. 171. no. 3976, pp. 1161 - 1163
DOI: 10.1126/science.171.3976.1161
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Articles

Acute Lymphocytic Leukemia in Owl Monkeys Inoculated with Herpesvirus saimiri

L. V. MelÉndez 1, R. D. Hunt 1, M. D. Daniel 1, B. Joan Blake 1, and F. G. Garcia 1

1 New England Regional Primate Research Center, Harvard Medical School, Southboro, Massachusetts

Our study demonstrates for the first time that Herpesvirus saimiri can induce acute lymphocytic leukemia in owl monkeys (Aotus trivirgatus) and that malignant lymphoma can be induced in this species of nonhuman primates by the inoculation of the virus by various routes (intravenous, sub-cutaneous, and intradermal).


THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES:
Activation of the Lck Tyrosine-protein Kinase by the Binding of the Tip Protein of Herpesvirus Saimiri in the Absence of Regulatory Tyrosine Phosphorylation.
D. A. Hartley, T. R. Hurley, J. S. Hardwick, T. C. Lund, P. G. Medveczky, and B. M. Sefton (1999)
J. Biol. Chem. 274, 20056-20059
   Abstract »    Full Text »    PDF »
Acute Leukemia with "Burkitt's Lymphoma Cells" and Burkitt's Lymphoma: Simultaneous Onset in American Siblings; Description of a New Entity.
D. A. STEVENS, G. T. O'CONOR, P. H. LEVINE, and R. B. ROSEN (1972)
Ann Intern Med 76, 967-973
   Abstract »    PDF »
Leukemia, Lymphoma, and Osteosarcoma Induced in the Syrian Golden Hamster by Simian Virus 40.
G. Th. Diamandopoulos (1972)
Science 176, 173-175
   Abstract »    PDF »


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Science. ISSN 0036-8075 (print), 1095-9203 (online)