Note to users. If you're seeing this message, it means that your browser cannot find this page's style/presentation instructions -- or possibly that you are using a browser that does not support current Web standards. Find out more about why this message is appearing, and what you can do to make your experience of our site the best it can be.

Science 12 March 1971:
Vol. 171. no. 3975, pp. 1037 - 1038
DOI: 10.1126/science.171.3975.1037
Prev | Table of Contents | Next

Articles

Dissociation of Impairment after Lateral and Medial Prefrontal Lesions in Dogs

Jadwiga Dabrowska 1

1 Department of Neurophysiology, Nencki Institute of Experimental Biology, Warsaw 22, Poland

Dogs were trained before operation on a go, no-go test with symmetrical reinforcement. Lesions situated on the medial surface of the prefrontal cortex caused slight or no impairment in retention, whereas removal of the lateral prefrontal cortex induced severe and long-lasting impairment. The lateral prefrontal cortex is probably related to selection of the proper instrumental responses to corresponding stimuli.


THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES:
Structural Abnormalities in the Frontal System in Schizophrenia: A Magnetic Resonance Imaging Study.
N. Andreasen, H. A. Nasrallah, V. Dunn, S. C. Olson, W. M. Grove, J. C. Ehrhardt, J. A. Coffman, and J. H. W. Crossett (1986)
Arch Gen Psychiatry 43, 136-144
   Abstract »    PDF »


To Advertise     Find Products

Science. ISSN 0036-8075 (print), 1095-9203 (online)