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Science 12 February 1971:
Vol. 171. no. 3971, pp. 581 - 583
DOI: 10.1126/science.171.3971.581
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Articles

Induction of Microsomal Oxidase in F1 Hybrids of a High and a Low Oxidase Housefly Strain

L. C. Terriere 1, S. J. Yu 1, and R. F. Hoyer 1

1 Department of Entomology, Oregon State University, Corvallis 97331

Microsomal oxidase activity is increased up to sixfold in dieldrin-resistant houseflies exposed to sublethal doses of dieldrin. The net increase in enzyme activity is greater in a strain initially high in oxidase activity than in a strain low in this respect, and this tendency is carried into the F1 hybrids of the strains.


THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES:
Metabolic Interactions Among Environmental Chemicals and Drugs: Environmental chemicals that alter microsomal activity may influence the safety and efficacy of drugs.
A. H. Conney and J. J. Burns (1972)
Science 178, 576-586
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Science. ISSN 0036-8075 (print), 1095-9203 (online)