Note to users. If you're seeing this message, it means that your browser cannot find this page's style/presentation instructions -- or possibly that you are using a browser that does not support current Web standards. Find out more about why this message is appearing, and what you can do to make your experience of our site the best it can be.

Science 5 February 1971:
Vol. 171. no. 3970, pp. 496 - 498
DOI: 10.1126/science.171.3970.496
Prev | Table of Contents | Next

Articles

Adenosine 3', 5'-Monophosphate Phosphodiesterase in the Growth Medium of Physarum polycephalum

Andrew W. Murray 1, Marqie Spiszman 1, and Daniel E. Atkinson 1

1 Biochemistry Division, Department of Chemistry, University of California, Los Angeles 90024

The acellular slime mold Physarum polycephalum releases a soluble adenosine 3', 5'-monophosphate phosphodiesterase into the growth medium. Although this enzyme resembles the particulate diesterase of the same organism in kinetic properties and in inhibition by methyl purines, its greater stability, its insensitivity to stimulation by imidazole and to inhibition by adenosine triphosphate,- and its selective release into the medium indicate a specific function, perhaps protection against exogenous cyclic nucleotide, for the soluble enzyme.


THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES:
Chemotherapy of parasitic worms: new biochemical strategies.
T. Mansour (1979)
Science 205, 462-469
   Abstract »    PDF »


To Advertise     Find Products

Science. ISSN 0036-8075 (print), 1095-9203 (online)