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Science 11 September 1970:
Vol. 169. no. 3950, pp. 1097 - 1098
DOI: 10.1126/science.169.3950.1097
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Articles

Cyclic Cytidine 2',3'-Phosphate: Molecular Structure

Charles L. Coulter 1 and Marsha L. Greaves 1

1 Department of Anatomy, University of Chicago, Chicago, Illinois 60637

Monoclinic crystals of the sodium salt of cytidine 2',3'-phosphate contain two anions in the asymmetric unit. Both bases are in the syn conformation, and the nucleotides are stacked together into an antiparallel stranded ribbon with the bases 3.3 angstroms apart. One ribose ring is planar, and the other has oxygen-1' puckered toward carbon-5'. The phosphorus atoms in the five-membered ester rings are puckered toward the sugars. The conformations about the carbon-4'—carbon-5' bonds are gauche-trans and gauche-gauche.

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Science. ISSN 0036-8075 (print), 1095-9203 (online)