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Science 11 September 1970:
Vol. 169. no. 3950, pp. 1091 - 1093
DOI: 10.1126/science.169.3950.1091
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Articles

Demyelinating Encephalomyelopathy Associated with Lead Poisoning in Nonhuman Primates

R. M. Sauer 1, B. C. Zook 2, and F. M. Garner 3

1 National Zoological Park Washington, D.C. 20009
2 Department of Pathology, School of Medicine, George Washington University, Washington, D.C. 20037
3 Armed Forces Institute of Pathology, Washington, D.C. 20305

Lead poisoning was diagnosed in four primates by the finding of toxic amounts of lead in tissues. Abnormalities in the brain and spinal cord were characterized by vascular lesions and demyelination. These findings suggest a new animal model for the study of demyelination and strengthen the supposition that lead may be a factor in some idiopathic demyelinating diseases.


THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES:
Scotopic vision deficits in young monkeys exposed to lead.
P. Bushnell, R. Bowman, Allen JR, and R. Marlar (1977)
Science 196, 333-335
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