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Science 11 September 1970:
Vol. 169. no. 3950, pp. 1088 - 1090
DOI: 10.1126/science.169.3950.1088
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Articles

Transmissible Mink Encephalopathy: Experimental Transmission to the Squirrel Monkey

Robert J. Eckroade 1, Gabriele M. Zu Rhein 1, Richard F. Marsh 2, and Robert P. Hanson 2

1 Department of Pathology, University of Wisconsin Medical School, Madison 53706
2 Department of Veterinary Science, University of Wisconsin, Madison

A progressive, fatal spongiform encephalopathy developed in three squirrel monkeys 11 months after inoculation with primate-passaged transmissible mink encephalopathy agent. The clinical symptoms and histopathologic and electron microscopic findings suggest that this naturally occurring disease of mink has been transmitted experimentally to squirrel monkeys.


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