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Science 4 September 1970:
Vol. 169. no. 3949, pp. 991 - 993
DOI: 10.1126/science.169.3949.991
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Articles

Homologous Viral Interference: Induction by RNA from Defective Particles of Vesicular Stomatitis Virus

T. Sreevalsan 1

1 Department of Microbiology, Georgetown University, Schools of Medicine and Dentistry, Washington, D.C. 20007

The viral RNA isolated from the defective particles of vesicular stomatitis virus was capable of interfering with the replication of this virus in chick embryo cells. The data indicate that the interfering ability of the defective particles of this virus is due to their nucleic acid component.

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Science. ISSN 0036-8075 (print), 1095-9203 (online)