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Science 31 July 1970:
Vol. 169. no. 3944, pp. 487 - 488
DOI: 10.1126/science.169.3944.487
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Articles

Antigen Receptor Molecules: Inhibition by Antiserum against Kappa Light Chains

Jayne Lesley 1 and Richard W. Dutton 1

1 Department of Biology, University of California, San Diego, La Jolla 92037

Rabbit antiserum against mouse kappa chains, the predominant class of light chains found in mouse immunoglobulins, inhibits the immune response in vitro of mouse spleen cells to erythrocyte antigens. The inhibition becomes irreversible if the mouse spleen cells are treated briefly with both antiserum to kappa chains and complement.


THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES:
Specific Suppression of Immune Responses.
D. A. Rowley, F. W. Fitch, F. P. Stuart, H. Kohler, and H. Cosenza (1973)
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Antibody-Dependent Lymphoid Cell-Mediated Cytotoxicity: No Requirement for Thymus-Derived Lymphocytes.
J. A. Van Boxel, J. D. Stobo, W. E. Paul, and I. Green (1972)
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Quantitative Aspects of Plasma Membrane-Associated Immunoglobulin in Clones of Diploid Human Lymphocytes.
R. A. Lerner, P. J. McConahey, and F. J. Dixon (1971)
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