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Science 24 July 1970:
Vol. 169. no. 3943, pp. 391 - 392
DOI: 10.1126/science.169.3943.391
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Articles

Genetic Polymorphisms of Human Mitochondrial Glutamic Oxaloacetic Transaminase

Ronald G. Davidson 1, Jean A. Cortner 1, Mario C. Rattazzi 1, Frank H. Ruddle 2, and Herbert A. Lubs 2

1 Division of Human Genetics, Children's Hospital of Buffalo, Buffalo, New York 14222
2 Departments of Biology and Medicine, Yale University, New Haven, Connecticut 06520

In a survey of 860 unselected human placental extracts, three variants of mitochondrial glutamic oxaloacetic transaminase were found, all of which were common enough to be considered polymorphisms. Family studies showed that this enzyme is under the control of nuclear rather than mitochondrial DNA.


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