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Science 12 June 1970:
Vol. 168. no. 3937, pp. 1361 - 1362
DOI: 10.1126/science.168.3937.1361

Articles

Primary Structures of Human Pituitary Growth Hormone and Sheep Pituitary Lactogenic Hormone Compared

Thomas A. Bewley 1 and Choh Hao Li 1

1 Hormone Research Laboratory, University of California, San Francisco

The primary structures of human pituitary growth hormone and sheep pituitary lactogenic hormone have been compared with regard to similarities in their sequence. Three homologous segments in each molecule, comprising approximately 45 percent of either peptide chain, have been found. These two proteins have apparently evolved from a common ancestor molecule.


THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES:
Identification of Growth Hormone in the Sea Lamprey, an Extant Representative of a Group of the Most Ancient Vertebrates.
H. Kawauchi, K. Suzuki, T. Yamazaki, S. Moriyama, M. Nozaki, K. Yamaguchi, A. Takahashi, J. Youson, and S. A. Sower (2002)
Endocrinology 143, 4916-4921
   Abstract »    Full Text »    PDF »
Primary Structure of the Human Chorionic Somatomammotropin (HCS) Molecule.
C. H. Li, J. S. Dixon, and D. Chung (1971)
Science 173, 56-58
   Abstract »    PDF »



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Science. ISSN 0036-8075 (print), 1095-9203 (online)