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Science 29 May 1970:
Vol. 168. no. 3935, pp. 1097 - 1098
DOI: 10.1126/science.168.3935.1097

Articles

Cigarette Smoke: The Effect of Residue on Mitochondrial Structure

John R. Kennedy 1 and Alfred M. Elliott 2

1 Department of Zoology, University of Tennessee, Knoxville 37916
2 Department of Zoology, University of Michigan, Ann Arbor 48104

Cigarette smoke residue is ciliatoxic to Tetrahymena pyriformis. Principal sites of activity are the mitochondria of the cell. The internal membranes of the mitochondria are degraded with time, correlating well with loss of ciliary activity and cell death.


THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES:
Cigarette smoke-induced blockade of the mitochondrial respiratory chain switches lung epithelial cell apoptosis into necrosis.
M. van der Toorn, D.-J. Slebos, H. G. de Bruin, H. G. Leuvenink, S. J. L. Bakker, R. O. B. Gans, G. H. Koeter, A. J. M. van Oosterhout, and H. F. Kauffman (2007)
Am J Physiol Lung Cell Mol Physiol 292, L1211-L1218
   Abstract »    Full Text »    PDF »
Induction of Pulmonary Edema and Emphysema in Cattle and Goats with 3-Methylindole.
J. R. Carlson, M. T. Yokoyama, and E. O. Dickinson (1972)
Science 176, 298-299
   Abstract »    PDF »



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Science. ISSN 0036-8075 (print), 1095-9203 (online)