On the Apparent Homology of Actin and Tubulin
R. E. Stephens 1
1 Department of Biology, Brandeis University, Waltham, Massachusetts, and The Marine Biological Laboratory, Woods Hole, Massachusetts 02543
Muscle actin and ciliary A-tubulin from Pecten irradians have molecular weights of 46,000 and 59,000, respectively, as measured by sodium lauryl sulfatepolyacrylamide-gel electrophoresis. Tryptic and chymotryptic peptides obtained from these proteins are very dissimilar, indicating that there is little significant homology.