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Science 17 April 1970:
Vol. 168. no. 3929, pp. 380 - 382
DOI: 10.1126/science.168.3929.380

Articles

Identity of Very Low Density Lipoprotein Apoproteins of Plasma and Liver Golgi Apparatus

R. W. Mahley 1, T. P. Bersot 1, V. S. Lequire 1, R. I. Levy 2, H. G. Windmueller 2, and W. V. Brown 3

1 Pathology Department, Vanderbilt University School of Medicine, Nashville, Tennessee 37203
2 National Institutes of Health, Bethesda, Maryland
3 Yale University Medical Center, New Haven, Connecticut

In the rat, very low density lipoproteins isolated from hepatocyte Golgi apparatus, liver perfusates, and whole plasma appear identical in many respects. With specific immunochemical techniques and polyacrylamide-gel electrophoresis it can be demonstrated that the very low density lipoproteins from all three sources contain the same major lipoprotein apoproteins.


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