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Science 20 February 1970:
Vol. 167. no. 3921, pp. 1134 - 1135
DOI: 10.1126/science.167.3921.1134
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Articles

[8-Arginine]-Vasopressinoic Acid: An Inhibitor of Rabbit Kidney Adenyl Cyclase

Tomas DouscaronA 1, Oscar Hechter 1, Roderich Walter 2, and I. L. Schwartz 2

1 American Medical Association Education and Research Foundation, Institute for Biomedical Research, 535 North Dearborn Street, Chicago, Illinois 60610
2 Department of Physiology, Mount Sinai Medical and Graduate Schools. New York 10029, and Medical Department, Brookhaven National Laboratory, Upton, New York 11973

Neurohypophyseal hormnones and several synthetic analogs stimulate adenyl cyclase prepared from rabbit kidney medullary tissue. [8-Arginine]-vasopressinoic acid inhibits the stimulation of medullary adenyl cyclase by neurohypophyseal peptides but does not influence the action of parathyroid hormone on adenyl cyclase from kidiney cortex.


THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES:
Uremic Toxins and Mineral Metabolism: Potential Sites of Interaction.
H. J. Gitelman (1970)
Arch Intern Med 126, 793-800
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Science. ISSN 0036-8075 (print), 1095-9203 (online)