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Science 5 December 1969:
Vol. 166. no. 3910, pp. 1291 - 1293
DOI: 10.1126/science.166.3910.1291
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Articles

Genetic Coding: Oligonucleotide Coding for First Six Amino Acid Residues of the Coat Protein of R17 Bacteriophage

William E. Robinson 1, Ramsey H. Frist 1, and Paul Kaesberg 2

1 Biophysics Laboratory, University of Wisconsin, Madison
2 Biophysics Laboratory and Department of Biochemistry, University of Wisconsin

Ribonucleic acids from the bacteriophage R17 and from R17 amber mutant AmB2 have been digested with ribonuclease T1. Of the products isolated, only one was different. It codes for the first six amino acid residues of the viral coat protein. The probable base sequence of the wild-type oligonucleotide is CpUpUpCpUpApApCpUpUpUpApCpUpCpApGp.

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Science. ISSN 0036-8075 (print), 1095-9203 (online)