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Science 5 December 1969:
Vol. 166. no. 3910, pp. 1282 - 1284
DOI: 10.1126/science.166.3910.1282

Articles

Altered Ribosomal Protein in Streptomycin-Dependent Escherichia coli

E. A. Birge 1 and C. G. Kurland 1

1 Department of Zoology, University of Wisconsin, Madison 53706

We have compared the 30S ribosomal proteins of strains of Escherichia coli sensitive to and dependent on streptomycin and identified a single protein that is functionally altered in the ribosomes dependent on streptomycin. This protein (30S-15) is the same protein that is functionally altered in ribosomes resistant to streptomycin.


THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES:
Accuracy modulating mutations of the ribosomal protein S4-S5 interface do not necessarily destabilize the rps4-rps5 protein-protein interaction.
H. Vallabhaneni and P. J. Farabaugh (2009)
RNA 15, 1100-1109
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Ribosome Structure and Function Emergent: Unexpected aspects of ribosome structure and function are revealed by studies of the ribosomal proteins.
C. G. Kurland (1970)
Science 169, 1171-1177
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