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Science 28 November 1969:
Vol. 166. no. 3909, pp. 1163 - 1165
DOI: 10.1126/science.166.3909.1163
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Articles

Herpes Simplex Virus: Dry Mass

Fritz Lampert 1, Gunter F. Bahr 1, and Alan S. Rabson 2

1 Biophysics Branch, Arrmed Forces Institute of Pathiology, Washington, D.C. 20305
2 Pathiologic Anatomiy Brancht, National Cancer Institute, Bethesda, Maryland 20014

Dry mass of herpes simplex virus particles was measured by quantitative electron microscopy after isolation by surface spreading and critical-point drying of infected cells. The core weighed about 2 x 10-16 gram, the empty naked capsid 5 x 10-16 gram, the full naked capsid 7 x 10-16 gram, and the enveloped nucleocapsid 13 x 10-16 gram.

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Science. ISSN 0036-8075 (print), 1095-9203 (online)