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Science 7 November 1969:
Vol. 166. no. 3906, pp. 747 - 749
DOI: 10.1126/science.166.3906.747
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Articles

Cell Sorting: Automated Separation of Mammalian Cells as a Function of Intracellular Fluorescence

H. R. Hulett 1, W. A. Bonner 1, Janet Barrett 1, and Leonard A. Herzenberg 1

1 Department of Getnetics, Statnford University School of Medicine, Stanford, California 94305

A system for high-speed sorting of fluorescent cells was able to sort mouse spleen cells from Chinese hamster ovarian cells after development of fluorochromasia. Highly fluorescent fractions separated after similar treatment from mouse spleen cells immunized to sheep erythrocytes were enriched in antibody-producing cells by factors of 4 to 10.


THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES:
Stem Cell Research: Paths to Cancer Therapies and Regenerative Medicine.
I. Weissman (2005)
JAMA 294, 1359-1366
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Quantitative single cell analysis and sorting.
P. Horan and L. Wheeless Jr (1977)
Science 198, 149-157
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Science. ISSN 0036-8075 (print), 1095-9203 (online)