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Science 17 October 1969:
Vol. 166. no. 3903, pp. 388 - 389
DOI: 10.1126/science.166.3903.388
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Articles

Luteinizing Hormone-Releasing Activity in Hypophysial Stalk Blood and Elevation by Dopamine

Ibrahim A. Kamberi 1, Renon S. Mical 1, and John C. Porter 1

1 Department of Physiology, University of Texas Southwestern Medical School at Dallas, Dallas 75235

Pituitary halves incubated in pituitary stalk plasma release more luteinizing hormone than their opposite halves incubated in plasma from peripheral blood. Glands incubated in stalk plasma from dopamine-treated rats release more luteinizing hormone than glands incubated in stalk plasma from untreated controls. Luteinizing hormone-releasing activity in stalk plasma may be due to the luteinizing hormone-releasing factor, and the secretion of luteinizing hormone-releasing factor may be controlled by a dopaminergic mechanism.


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