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Science 10 October 1969:
Vol. 166. no. 3902, pp. 252 - 253
DOI: 10.1126/science.166.3902.252
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Articles

Skin Replication Procedure for the Scanning Electron Microscope

Emil O. Bernstein 1 and Chase B. Jones 2

1 Gillette Research Institute, Rockville, Maryland 20850
2 Gillette Toiletries Company, Boston, Massachusetts 02106

Ani improved method for preparing polyethylene replicas of skin from silicone rubber molds was developed for examination in the scanning electron microscope. Electro micrographs of the replicas compare favorably to those of fixed tissues from the same animal. Because of the great depth of field of the scanning electron microscope, both loosely attached epidermal cells and the background epidermal surface can be seen simultaneously in sharp focus, thus providing, a more complete picture of the topography of skin.


THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES:
Direct Scanning Electron Microscopy Human Skin.
C. M. Papa and B. Farber (1971)
Arch Dermatol 104, 262-270
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Science. ISSN 0036-8075 (print), 1095-9203 (online)