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Science 10 October 1969:
Vol. 166. no. 3902, pp. 239 - 240
DOI: 10.1126/science.166.3902.239
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Articles

Allergenic Component of a Liverwort: A Sesquiterpene Lactone

H. Knoche 1, G. Ourisson 1, G. W. Perold 1, J. Foussereau 2, and J. Maleville 2

1 Laboratoire Associé au CNRS, Institut de Chimie, 67-Strasbourg, France
2 Clinique Dermatologique, Hôpital Civil, 67-Strasbourg

Frullania spp. (Hepaticae, Jungermanniales) are agents of allergies. Extraction and fractionation of Frullania tamarisci has given, as the only allergenic component isolated, a levorotatory crystalline sutbstance, the structure of which is demonstrated. It is a sesquiterpene lactone. The racemic (±) form is isolated from a mixed sample of Frullania tamarisci and Frullania dilatata; the dextrorotatory form, from Frullania dilatata. The observed allergenic properties are shared by some other-sesquiterpene lactones.


THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES:
Cross-Sensitization Between Frullania and Laurus nobilis: The Allergen Laurel.
Y. Asakawa, C. Benezra, G. Ducombs, J. Foussereau, J. C. Muller, and G. Ourisson (1974)
Arch Dermatol 110, 957
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