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Science 26 September 1969:
Vol. 165. no. 3900, pp. 1374 - 1375
DOI: 10.1126/science.165.3900.1374
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Articles

Cellular Response to Ecdysterone in vitro

Kenneth J. Judy 1

1 U.S. Agricultural Research Service, State University Station, Fargo, North Dakota 58102

Organ cultures of hindgut from diapausing tobacco hornworm pupae, Manduca sexta (Johannson), produce an abundance of migrant cells around the original explant. With time-lapse cinematography, these cells were seen to move slowly and tended to aggregate. The addition of ecdysterone (beta-ecdysone) to these cultures stimulated a large increase in individual cell movements and the eventual disruption of cell sheets.

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Science. ISSN 0036-8075 (print), 1095-9203 (online)