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Science 12 September 1969:
Vol. 165. no. 3898, pp. 1131 - 1133
DOI: 10.1126/science.165.3898.1131
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Articles

Nerve Endings: Rapid Appearance of Labeled Protein Shown by Electron Microscope Radioautography

Bernard Droz 1 and Samuel H. Barondes 2

1 Departement de Biologie, Commissariat á l'Energie Atomique, 91 Saclay, France
2 Department of Psychiatry, Albert Einstein College of Medicine, Bronx, New York 10461

Electron microscope radioautographs of nerve ending fractions from mouse cerebrum show that radioactive protein is associated with nerve endings 15 and 90 minutes after intracerebral injection of tritiated leucine and lysine. The results are consistent with synthesis of protein at nerve endings, or with extremely rapid transport of particulate protein to nerve endings in the mouse cerebrum, or both.


THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES:
Local Gene Expression in Axons and Nerve Endings: The Glia-Neuron Unit.
A. Giuditta, J. Tai Chun, M. Eyman, C. Cefaliello, A. P. Bruno, and M. Crispino (2008)
Physiol Rev 88, 515-555
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Science. ISSN 0036-8075 (print), 1095-9203 (online)