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Science 15 August 1969:
Vol. 165. no. 3894, pp. 705 - 706
DOI: 10.1126/science.165.3894.705
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Articles

Microsome-Associated DNA

Howard E. Bond 1, John A. Cooper II 1, Doris P. Courington 1, and Jeannie S. Wood 1

1 Laboratory of Biology, National Cancer Institute, Bethesda, Maryland 20014

Deoxyribonucleic acid has been isolated from the microsomes of mouse liver homogenates under conditions designed to prevent or greatly reduce mitochondrial and nuclear contamination. The DNA rapidly incorporates tritiated thymidine, and this, together with its reannealing characteristics after thermal denaturation, shows that it is not mitochondrial or typically nuclear DNA.


THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES:
DNA Polymerase Activities Associated with Smooth Membranes and Ribosomes from Rat Liver and Hepatoma Cytoplasm.
E. F. Baril, M. D. Jenkins, O. E. Brown, and J. Laszlo (1970)
Science 169, 87-89
   Abstract »    PDF »
Cytoplasmic Extraction: Polyribosomes and Heterogeneous Ribonucleoproteins without Associated DNA.
D. Fromson and M. Nemer (1970)
Science 168, 266-267
   Abstract »    PDF »


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