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Science 1 August 1969:
Vol. 165. no. 3892, pp. 510 - 512
DOI: 10.1126/science.165.3892.510
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Articles

Crystalline L-Asparaginase from Escherichia coli B

Peter P. K. Ho 1, Bruce H. Frank 1, and Philip J. Burck 1

1 Lilly Research Laboratories, Eli Lilly and Company, Indiananapolis, Iindiana 46206

L-Asparaginase has been crystallized from a partially purified extract of Escherichia coli B. The crystalline enzyme is homogeneous, as judged by analytical polyacrylamidegel electrophoresis and sedimentation behavior. This enzyme preparation is active in preventing lymphoma in mice and also has low glutaminase activity.


THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES:
L-Asparaginase: Clinical, Biochemical, Pharmacological, and Immunological Studies.
R. L. CAPIZZI, J. R. BERTINO, R. T. SKEEL, W. A. CREASEY, R. ZANES, C. OLAYON, R. G. PETERSON, and R. E. HANDSCHUMACHER (1971)
Ann Intern Med 74, 893-901
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