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Science 25 July 1969:
Vol. 165. no. 3891, pp. 394 - 396
DOI: 10.1126/science.165.3891.394
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Articles

Transplantation of Pluripotential Nuclei from Triploid Frog Tumors

Robert G. McKinnell 1, Beverly A. Deggins 1, and Deidre D. Labat 1

1 Department of Biology, Newcomb College of Tulane University, New Orleans, Louisiana 70118

Renal tumors were produced by injection of a cell fraction of a tumor into triploid tadpoles of Rana pipiens before they began feeding. Triploid tumor cells were dissociated and transplanted into activated and enucleated eggs. Pluripotency of the implanted nuclei was evidenced by the formation of swimming triploid tadpoles.


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