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Science 18 July 1969:
Vol. 165. no. 3890, pp. 300 - 302
DOI: 10.1126/science.165.3890.300

Articles

Human Leukocyte Antigenic Specificity HL-A3: Frequency of Occurrence

Bernard Amos 1 and Edmond Yunis 1

1 Duke University Medical Center, Durham, North Carolina 27706, and University of Minnesota Medical Center, Minneapolis 55455

Reactivity of antiserum against HL-A3, a human leukocyte and tissue antigenic specificity, depends upon a property of the lymphocyte as well as on the potency of the serum. Many reactions of HL-A3 antiserums can only be recognized through absorption or by a two-stage test not in general use. Interpretations of donor-recipient compatibility and of the constitution of HL-A alleles affected by these findings.





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Science. ISSN 0036-8075 (print), 1095-9203 (online)