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Science 11 July 1969:
Vol. 165. no. 3889, pp. 192 - 194
DOI: 10.1126/science.165.3889.192
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Articles

High-Resolution Autoradiography of Intracellular Plutonium

Arthur Lindenbaum 1 and Martin H. Smoler 1

1 Division of Biological and Medical Research, Argonne National Laboratory, Argonne, Illinois 60439

Intracellular incorporation of polymeric plutonium injected into mice was demonstrated in liver and spleen by electron-microscopic auto-radiography. The observations are not inconsistent with other evidence indicating the association of plutonium with lysosomal components. Early results with a quantitative electron-microscopic technique may lead to microdosimetry of cells and cellular components.

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Science. ISSN 0036-8075 (print), 1095-9203 (online)