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Science 25 April 1969:
Vol. 164. no. 3878, pp. 442 - 443
DOI: 10.1126/science.164.3878.442

Articles

Circadian Rhythm of Serotonin in the Pineal Body of Immunosympathectomized Immature Rats

Conceicao R. S. Machado 1, Laurence E. Wragg 1, and Angelo B. M. Machado 1

1 Department of Biostructure, Northwestern University, Chicago, Illinois 60611

In the pineal body of the immature rat the circadian rhythm of serotonin persists when sympathetic innervation is abolished by the administration of nerve growth factor antiserum. This rhythm is regulated by a mechanism that does not involve the sympathetic innervation and is, therefore, fundamentally different from that in the adult.


THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES:
Developmental Expression Pattern of Phototransduction Components in Mammalian Pineal Implies a Light-Sensing Function.
S. Blackshaw and S. H. Snyder (1997)
J. Neurosci. 17, 8074-8082
   Abstract »    Full Text »    PDF »
Induction of photosensitivity in neonatal rat pineal gland.
G. Tosini, S. Doyle, M. Geusz, and M. Menaker (2000)
PNAS 97, 11540-11544
   Abstract »    Full Text »    PDF »



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Science. ISSN 0036-8075 (print), 1095-9203 (online)