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Science 14 February 1969:
Vol. 163. no. 3868, pp. 693 - 695
DOI: 10.1126/science.163.3868.693
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Articles

Nucleotide Sequence of Escherichia coli Tyrosine Transfer Ribonucleic Acid

B. P. Doctor 1, Judith E. Loebel 1, Mary Ann Sodd 1, and David B. Winter 1

1 Division of Biochemistry, Walter Reed Army Institute of Research, Washington, D.C. 20012

The nucleotide sequence of one of the Escherichia coli tyrosine-transfer ribonucleic acids was determined in order to compare its sequence with that of yeast tyrosine-transfer ribonucleic acid. Forty-four positions of both transfer ribonucleic acids are occupied by the same nucleotides if they are arranged in the manner shown here. The information obtained suggests that the conformation of transfer ribonucleic acid molecules may be a greater contributing factor than a specific nucleotide sequence in the interaction of transfer ribonucleic acid with its corresponding aminoacyl-transfer ribonucleic acid synthetase.


THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES:
An Historical Account of Protein Synthesis, with Current Overtones--A Personalized View.
P. C. Zamecnik (1969)
Cold Spring Harb Symp Quant Biol 34, 1-16
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Science. ISSN 0036-8075 (print), 1095-9203 (online)