Genetics of Diego Blood Groups in Guatemalan Indians: Use of Antiserums to Diego a and Diego b Antigens
Howard M. Cann 1,
Betty Van West 1, and
Clifford R. Barnett 1
1 Department of Pediatrics and Human Development, Stanford University School of Medicine, Palo Alto, California 94304
Red blood cells of 255 inhabitants of San Antonio Palopo, an Indian community on the eastern shore of Lake Atitlán, Guatemala, have been typed with antiserum.. to Diego a (Dia) and the newly discovered antiserum to Dib. Individuals with erythrocyte antigenic types Di(a+ b-, Di(a+ b+), and Di(a-b+) have been found, but the type Di(a-b-) has not been encountered. Population frequencies of antigenic types and family studies support the hypothesis that the erythrocyte antigens, Die and Dib, are controlled by two codominant alleles at a single autosomal locus.