Note to users. If you're seeing this message, it means that your browser cannot find this page's style/presentation instructions -- or possibly that you are using a browser that does not support current Web standards. Find out more about why this message is appearing, and what you can do to make your experience of our site the best it can be.

Science 13 December 1968:
Vol. 162. no. 3859, p. 1295
DOI: 10.1126/science.162.3859.1295
Prev | Table of Contents | Next

Articles

Mice Unilaterally Sensitized for Audiogenic Seizures

John L. Fuller 1 and Robert L. Collins 1

1 Jackson Laboratory, Bar Harbor, Maine

Strain SJL/J mice exposed to loud bell-ringing (primed) with one ear blocked do not convulse, but are susceptible to audiogenic seizures 48 hours later when stimulated only through the ear open at priming. Mice stimulated through the ear blocked at priming do not convulse, but are convulsible when retested on the opposite ear. The site of sensitization appears to be either in the ear or in those portions of the auditory system receiving input only from one side.


THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES:
Unilateral Increase of Auditory Sensitivity following Early Auditory Exposure.
K. R. Henry (1972)
Science 176, 689-690
   Abstract »    PDF »
Unilateral Inhibition of Sound-Induced Couvulsions in Mice.
R. L. Collins (1970)
Science 167, 1010-1011
   Abstract »    PDF »


To Advertise     Find Products

Science. ISSN 0036-8075 (print), 1095-9203 (online)