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Science 1 November 1968:
Vol. 162. no. 3853, pp. 580 - 582
DOI: 10.1126/science.162.3853.580
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Articles

Hypothalamic Stimulation of Growth Hormone Secretion

Lawrence A. Frohman 1, Lee L. Bernardis 1, and kenneth J. Kant 1

1 Departments of Medicine, Pathology, and Physiology, State University of New York at Buffalo, Buffalo 14215

Stimulation of the ventromedial hypothalamic nucleus in rats resulted in increased plasma growth hormone levels within 5 minutes, as measured by radioimmunoassay. Stimulation of the cerebral cortex was without effect. These observations confirm previous results involving destructive lesions and establish the ventromedial nucleus as a hypothalamic locus involved in the control of growth hormone secretion.


THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES:
Pulsatile Growth Hormone Secretion: Suppression by Hypothalamic Ventromedial Lesions and by Long-Acting Somatostatin.
J. B. Martin, L. P. Renaud, and P. Brazeau Jr. (1974)
Science 186, 538-540
   Abstract »    PDF »
Thyrotropin Secretion in Rats after Hypothalamic Electrical Stimulation or Injection of Synthetic TSH-Releasing Factor.
J. B. Martin and S. Reichlin (1970)
Science 168, 1366-1368
   Abstract »    PDF »
Hypothalamic Stimulation of Growth Hormone Secretion.
G. P. Smith, A. W. Root, L. A. Frohman, L. L. Bernardis, and K. J. Kant (1969)
Science 163, 705
   PDF »


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