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Science 25 October 1968:
Vol. 162. no. 3852, pp. 452 - 454
DOI: 10.1126/science.162.3852.452
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Articles

Chemical Sensing: An Approach to Biological Molecular Mechaisms Using Difference Spectroscopy

K. Owen Ash 1

1 Honeywell Corporate Research Center, 500 Washington Avenue South, Hopkins, Minnesota 55343

Stimulation of preparations of rabbit olfactory epithelium with aqueous solutions containing the odorants linalool or inalyl isobutyrate, or both, initiates molecular changes that can be monitored by a specific decrease in absorbance at 267 nanometers. This change in absorbance appears to be associated with a change in macromolecular conformation which is initiated by formation of a complex involving the stimulant molecules.


THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES:
Ascorbic Acid: Cofactor in Rabbit Olfactory Preparations.
K. O. Ash (1969)
Science 165, 901-902
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Science. ISSN 0036-8075 (print), 1095-9203 (online)