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Science 18 October 1968:
Vol. 162. no. 3851, pp. 367 - 368
DOI: 10.1126/science.162.3851.367
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Articles

Hydroxyindole-O-Methyl-Transferase Activity: Effect of Sympathetic Nerve Stimulation

Michael J. Brownstein 1 and Alfred Heller 1

1 Department of Pharmacology, University of Chicago, Chicago, Illinois 60637

Stimulation of the preganglionic nerve trunk to the superior cervical ganglion causes a reduction in pineal hydroxyindole-O-methyl-transferase levels which is time-dependent. The results provide direct evidence for a role of afferent input in the control of pineal enzymatic activity.


THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES:
Pineal N-Acetyltransferase Activity: Effect of Sympathetic Stimulation.
P. H. Volkman and A. Heller (1971)
Science 173, 839-840
   Abstract »    PDF »
Indole Metabolism in the Pineal Gland: A Circadian Rhythm in N-Acetyltransferase.
D. C. Klein and J. L. Weller (1970)
Science 169, 1093-1095
   Abstract »    PDF »


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