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Science 11 October 1968:
Vol. 162. no. 3850, pp. 279 - 281
DOI: 10.1126/science.162.3850.279-a
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Articles

Long-Lasting Hyperpolarization after Activity of Neurons in Leech Central Nervous System

J. G. Nicholls 1 and D. A. Baylor 1

1 Department of Physiology, Yale University School of Medicine, New Haven, Connecticut 06510

After a train of impulses, the membrane potential of sensory neurons may be increased for several minutes by an electrogenic pump. During this hyperpolarization, the sensitivity of the membrane potential to external potassium ions is increased, so that physiologically occurring increases in potassium concentration could influence synaptic processes.

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Science. ISSN 0036-8075 (print), 1095-9203 (online)