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Science 4 October 1968:
Vol. 162. no. 3849, pp. 129 - 130
DOI: 10.1126/science.162.3849.129

Articles

Corneal Calcification

Ben S. Fine 1, Joseph W. Berkow 2, and Samuel Fine 3

1 Ophthalmic Pathology Branch, Armed Forces Institute of Pathology, Washington, D.C. 203,05, and Department of Ophthalmnology, George Washington University Medical Center, Washington, D.C.
2 Ophthalmic Pathology Branch, Armed Forces Institute of Pathology
3 Department of Biophysics and Bio-Medical Engineering, Northeastern University, Boston, Massachusetts

Superficial calcification was produced in the normal rabbit cornea by mild irradiation with a carbon dioxide laser. The calcification was entirely extracellular and closely resemnbled that observed in human band keratopathy, which was characterized as hydroxyapatite by x-ray diffraction. The electron-mnicroscopic appearance of calcific spheriules and conglomerates in early cornteal calcification is presented. The calcific spherules arise at the basal plasma membrane surface of the epithelial cells in close relation to their basement membrane.


THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES:
Acute Band Keratopathy Following Intracameral Viscoat.
A. S. Nevyas, I. M. Raber, R. C. Eagle Jr, I. B. Wallace, and H. J. Nevyas (1987)
Arch Ophthalmol 105, 958-964
   Abstract »    PDF »
Energy Dispersive X-ray Analysis of the Cornea: Application to Paraffin Sections of Normal and Diseased Corneas.
M. R. Robinson and B. W. Streeten (1984)
Arch Ophthalmol 102, 1678-1682
   Abstract »    PDF »



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